2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Drug Metabolite

Drug Metabolite

Drug Metabolite

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Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-118093R
    N-benzoyl-L-aspartic acid (Standard)
    N-benzoyl-L-aspartic acid (Standard) is the analytical standard of N-benzoyl-L-aspartic acid. This product is intended for research and analytical applications. N-benzoyl-L-aspartic acid, a major metabolite of benzyl glucosinolate, can be used for modification of peptides or proteins.
    N-benzoyl-L-aspartic acid (Standard)
  • HY-W1006349
    1,2,3,4,6,7,8-Heptachlorodibenzofuran
    1,2,3,4,6,7,8-Heptachlorodibenzofuran (1,2,3,4,6,7,8-HpCDF) is a dioxin-like polychlorinated dibenzofuran (PCDF). 1,2,3,4,6,7,8-Heptachlorodibenzofuran has been found in the soil near municipal waste incinerators, in freshwater fish, and in human breastmilk.
    1,2,3,4,6,7,8-Heptachlorodibenzofuran
  • HY-17412B
    4-Epiminocycline
    4-Epiminocycline is a Minocycline (HY-17412A) degradation product. Minocycline (HY-17412A) is an antibiotic that has anti-inflammatory, anticancer, antibacterial, immunomodulatory and neuroprotective effects.
    4-Epiminocycline
  • HY-W009713R
    3,4,5-Trimethoxyphenylacetic acid (Standard)
    Cyclogalegenin (Standard) is the analytical standard of Cyclogalegenin. This product is intended for research and analytical applications. Cyclogalegenin (Cyclogalegigenin) is a isoprenoid that can be isolated from Astragalus galegiformis. Cyclogalegenin is the enantiomer of Cycloastragenol.
    3,4,5-Trimethoxyphenylacetic acid (Standard)
  • HY-W716866
    10α-Hydroxy-exo-THC
    10α-hydroxy-exo-THC is a cannabinoid compound, a metabolite of Δ9-THC, and can be found in cannabis. 10α-hydroxy-exo-THC can serve as an analytical reference standard for cannabinoid compounds .
    10α-Hydroxy-exo-THC
  • HY-167643
    Hydroxy tipelukast
    Hydroxy tipelukast (Compound MN-002), the metabolite of Compound MN-001, is an orally active phenoxyalkylcarboxylic acid. Hydroxy tipelukast inhibits liver steatosis, lobular inflammation, hepatic ballooning, and hepatic scarring, and reduces liver hydroxyproline levels. Hydroxy tipelukast is promising for research of non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH).
    Hydroxy tipelukast
  • HY-W293109
    AB-PINACA 3-Carboxyindazole metabolite
    		Control
    AB-PINACA 3-Carboxyindazole metabolite is a metabolite of APINAC.
    AB-PINACA 3-Carboxyindazole metabolite
  • HY-W700665
    5-Hydroxy indomethacin
    5-Hydroxy indomethacin (O-Desmethyl indomethacin) is a metabolite of Indomethacin (HY-14397).
    5-Hydroxy indomethacin
  • HY-W017115
    4-Methoxybenzenecarbothioamide
    4-Methoxybenzenecarbothioamide is a synthetic intermediate useful for pharmaceutical synthesis, which can be synthesized by 4-methoxy benzamide and phosphorus pentasulfide reactions.
    4-Methoxybenzenecarbothioamide
  • HY-121899R
    1-Oxo Ibuprofen (Standard)
    1-Oxo Ibuprofen (Standard) is the analytical standard of 1-Oxo Ibuprofen. This product is intended for research and analytical applications. 1-Oxo Ibuprofen (Ibuprofen EP impurity J) is a degradation product and a potential impurity in preparations of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively.
    1-Oxo Ibuprofen (Standard)
  • HY-W008216R
    HMMNI (Standard)
    HMMNI (Standard) (Hydroxy Dimetridazole (Standard)) is the analytical standard of HMMNI (HY-W008216). This product is intended for research and analytical applications. HMMNI (Hydroxy dimetridazole) is a hydroxy metabolite of Dimetridazol (HY-B1244). Dimetridazole is a nitroimidazole class drug that combats protozoan infections.
    HMMNI (Standard)
  • HY-113257
    Dopamine 4-sulfate
    Dopamine 4-sulfate (DA-4S) is an inactive metabolite of the catecholamine dopamine. It is formed from dopamine by the sulfotransferase (SULT) isoform SULT1A3. Dopamine 4-O-sulfate is found at lower levels in the brain and circulation than dopamine 3-O-sulfate.
    Dopamine 4-sulfate
  • HY-W654227
    7-Hydroxy methotrexate-d3 ammonium salt
    7-Hydroxy methotrexate-d3 (ammonium salt) is deuterium labeled 7-Hydroxymethotrexate. 7-Hydroxymethotrexate is a major metabolite of Methotrexate (MTX; HY-14519). Methotrexate, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis.
    7-Hydroxy methotrexate-d<sub>3</sub> ammonium salt
  • HY-W104075
    2-Amino-5-bromo-2’-chlorobenzophenone
    		Control
    2-Amino-5-bromo-2’-chlorobenzophenone is a precursor in the synthesis of Phenazepam.1 2-Amino-5-bromo-2’-chlorobenzophenone is also an active metabolite of Phenazepam.
    2-Amino-5-bromo-2’-chlorobenzophenone
  • HY-139433
    6-Hydroxy etodolac
    6-Hydroxy etodolac (compound 2) is a metabolite of Etodolac (HY-76251). Etodolac is a non-steroidal anti-inflammatory compound and is a COX inhibitor.
    6-Hydroxy etodolac
  • HY-135577
    β-Apooxytetracycline
    		≥99.0%
    β-Apooxytetracycline is a degradation product of Oxytetracycline (HY-B0275). Oxytetracycline is a widespread antibiotic.
    β-Apooxytetracycline
  • HY-100085R
    21-Desacetyldeflazacort (Standard)
    21-Desacetyldeflazacort (Standard) is the analytical standard of 21-Desacetyldeflazacort. This product is intended for research and analytical applications. 21-Desacetyldeflazacort (21-desDFZ) is the active metabolite of Deflazacort (HY-13609). Deflazacort is an anti-inflammatory and immunosuppressant. Deflazacort is an inactive pro-drug which can be rapidly converted by esterases to the active metabolite 21-desacetyldeflazacort after oral administration.
    21-Desacetyldeflazacort (Standard)
  • HY-W278566
    Saluamine
    		99.75%
    Saluamine is a metabolite of Furosemide (HY-B0135).
    Saluamine
  • HY-W009265
    4-Octylphenol diethoxylate
    4-Octylphenol diethoxylate (Octoxynol-2) is an endogenous estradiol like endocrine disrupter. 4-Octylphenol diethoxylate is the water contaminant.
    4-Octylphenol diethoxylate
  • HY-12765R
    Losartan Carboxylic Acid (Standard)
    Losartan Carboxylic Acid (Standard) is the analytical standard of Losartan Carboxylic Acid. This product is intended for research and analytical applications. Losartan Carboxylic Acid (E-3174), an active carboxylic acid metabolite of Losartan, is an angiotensin II receptor type 1 (AT1) antagonist. The Ki values are 0.97, 0.57, 0.67 nM for rat AT1B/AT1A and human AT1, respectively. Losartan Carboxylic Acid blocks the angiotensin II-induced responses in vascular smoothmuscle cells (VSMC). Losartan Carboxylic Acid elevates plasma renin activities and reduces mean arterial pressure[4].
    Losartan Carboxylic Acid (Standard)
Cat. No. Product Name / Synonyms Application Reactivity